Active Public Health Outbreaks in Oklahoma: November 2025 Report

CRITICAL ALERT: Equine Herpesvirus (EHV-1)

Status: Active & Expanding

A significant outbreak of Equine Herpesvirus (EHV-1), including the neurological strain (EHM), is currently affecting Oklahoma. Traced to a rodeo event in Waco, Texas (Nov 5-9, 2025), cases have been confirmed in Oklahoma, Mayes, Payne, and Logan counties.

Event Cancellations

Barrel Futurities of America World Championship at Lazy E Arena (Guthrie) canceled.

H5N1 Avian Influenza

Status: Persistent Surveillance

Confirmed positive cases in backyard flocks in Grady and McClain counties as of mid-November 2025. While the CDC maintains the public health risk is "low," the virus's persistence in dairy cattle and sporadic human cases (including a fatality in neighboring Louisiana earlier this year) keeps health officials on high alert.

Respiratory Season (Flu/RSV)

Status: Early Season Rise

RSV activity is increasing across the South, specifically impacting children aged 0-4. Influenza levels are "low but rising."

Data Discrepancy: Official CDC clinical data reporting has been impacted by a federal government shutdown in late 2025, leaving wastewater monitoring as a more current indicator than hospital reporting.

Detailed Analysis: The Data Gap & Conflicting Viewpoints

A critical finding in the November 2025 public health landscape is a divergence in data sources due to administrative disruptions. While state-level alerts from the Oklahoma State Department of Health (OSDH) remain active for specific outbreaks like EHV-1, national respiratory data streams have faced interruptions.

Official Clinical Data (CDC/State)

  • Reports "Low" activity for COVID-19 and Flu nationally.
  • Relies on hospital admission data which has lagged due to the reported government shutdown in late 2025.
  • Viewpoint: Focuses on hospital capacity and severe outcomes, currently suggesting a manageable start to the winter season.

Wastewater & Private Surveillance (Biobot)

  • Indicates increasing viral loads for RSV and Influenza A in the Southern region.
  • Highlights a "blind spot" in clinical data since late September 2025.
  • Viewpoint: Suggests community transmission is higher than official case counts imply, urging earlier preventative caution.

Ongoing Chronic Health Challenges

Disease Current Status (Nov 2025) Primary Risk Group Trend
Syphilis (Congenital) Severe, long-term surge. Oklahoma rates remain among the highest in the nation. Newborns, Native American communities ? Critical
West Nile Virus Season ending. 53 confirmed cases in 2025. Adults > 50, Outdoor workers ? Declining
Measles Sporadic. 1,798 US cases in 2025; OK listed as having cases but no active massive cluster in Nov. Unvaccinated children, Travelers ? Stable/Vigilant

Timeline: November 2025 EHV-1 Outbreak

Nov 5-9, 2025

Exposure Event

WPRA World Finals in Waco, TX. Horses from multiple states exposed.

Nov 19-21, 2025

Oklahoma Detections

Positive cases confirmed in Oklahoma, Mayes, and Payne counties. Neurologic signs (EHM) observed.

Nov 22, 2025

Major Cancellation

Barrel Futurities of America World Championship at Lazy E Arena canceled to prevent spread.

Respiratory Virus Threat Level (Oklahoma)

RSV (Children 0-4) Moderate-High
Influenza (General) Low but Rising
COVID-19 Low

Based on wastewater signal & available emergency department data as of Nov 30, 2025.